TY - GEN AU - Simmet,V AU - Eberst,L AU - Marabelle,A AU - Cassier,P A TI - Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials? SN - 1569-8041 PY - 2020///0803 KW - Antineoplastic Agents, Immunological KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - B7-H1 Antigen KW - antagonists & inhibitors KW - CTLA-4 Antigen KW - Clinical Trials, Phase I as Topic KW - standards KW - Dose-Response Relationship, Drug KW - Humans KW - Maximum Tolerated Dose KW - Neoplasms KW - drug therapy KW - Programmed Cell Death 1 Receptor KW - Protein Kinase Inhibitors KW - Research Design KW - Treatment Outcome N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1093/annonc/mdz286 ER -