TY - GEN AU - Hohl,Adrian AU - Karan,Ram AU - Akal,Anastassja AU - Renn,Dominik AU - Liu,Xuechao AU - Ghorpade,Seema AU - Groll,Michael AU - Rueping,Magnus AU - Eppinger,Jörg TI - Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen SN - 2045-2322 PY - 2020///1102 KW - Amino Acyl-tRNA Synthetases KW - chemistry KW - Flow Cytometry KW - methods KW - Gene Library KW - High-Throughput Screening Assays KW - Lysine KW - analogs & derivatives KW - Molecular Conformation KW - Molecular Docking Simulation KW - Molecular Dynamics Simulation KW - Protein Engineering KW - Structure-Activity Relationship KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-019-48357-0 ER -