TY - GEN AU - Kitcher,Siân R AU - Kirkwood,Nerissa K AU - Camci,Esra D AU - Wu,Patricia AU - Gibson,Robin M AU - Redila,Van A AU - Simon,Julian A AU - Rubel,Edwin W AU - Raible,David W AU - Richardson,Guy P AU - Kros,Corné J TI - ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity SN - 2379-3708 PY - 2020///0831 KW - Amikacin KW - toxicity KW - Aminoglycosides KW - Animals KW - Anti-Bacterial Agents KW - Antineoplastic Agents KW - Cell Culture Techniques KW - Cells, Cultured KW - Cisplatin KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Hair Cells, Auditory KW - drug effects KW - Humans KW - Intravital Microscopy KW - Ion Channels KW - antagonists & inhibitors KW - Male KW - Mechanotransduction, Cellular KW - Mice KW - Ototoxicity KW - etiology KW - Patch-Clamp Techniques KW - Protective Agents KW - pharmacology KW - Rats KW - Thiophenes KW - Time-Lapse Imaging KW - Urea KW - analogs & derivatives KW - Zebrafish N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media UR - https://doi.org/10.1172/jci.insight.126764 ER -