TY  - GEN
AU  - Absi,Mais
AU  - Eid,Basma G
AU  - Ashton,Nick
AU  - Hart,George
AU  - Gurney,Alison M
TI  - Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism
SN  - 1932-6203
PY  - 2020///0309
KW  - 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
KW  - pharmacology
KW  - Animals
KW  - Calcium Channel Blockers
KW  - Calcium Channels
KW  - drug effects
KW  - Disease Models, Animal
KW  - Endothelium, Vascular
KW  - Hydroxymethylglutaryl-CoA Reductase Inhibitors
KW  - Male
KW  - Muscle Relaxation
KW  - Muscle, Smooth, Vascular
KW  - Nitric Oxide Synthase Type III
KW  - antagonists & inhibitors
KW  - Phenylephrine
KW  - Pulmonary Arterial Hypertension
KW  - drug therapy
KW  - Pulmonary Artery
KW  - Rats
KW  - Rats, Wistar
KW  - Simvastatin
KW  - rho-Associated Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0220473
ER  -