Absi, Mais <br/><br/>
Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism.  [electronic resource] 

 -  PloS one  2019 
 - e0220473 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0220473  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid--pharmacology<br/>Animals<br/>Calcium Channel Blockers--pharmacology<br/>Calcium Channels--drug effects<br/>Disease Models, Animal<br/>Endothelium, Vascular--drug effects<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology<br/>Male<br/>Muscle Relaxation--drug effects<br/>Muscle, Smooth, Vascular--drug effects<br/>Nitric Oxide Synthase Type III--antagonists & inhibitors<br/>Phenylephrine--pharmacology<br/>Pulmonary Arterial Hypertension--drug therapy<br/>Pulmonary Artery--drug effects<br/>Rats<br/>Rats, Wistar<br/>Simvastatin--pharmacology<br/>rho-Associated Kinases--antagonists & inhibitors