Abd El-Aleam, Rehab H <br/><br/>
Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity.  [electronic resource] 

 -  Archiv der Pharmazie  Aug 2019 
 - e1900002 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-4184 
<br/><br/><label>Standard No.: </label>10.1002/ardp.201900002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Bronchodilator Agents--chemical synthesis<br/>Cyclic Nucleotide Phosphodiesterases, Type 4--metabolism<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Humans<br/>Male<br/>Molecular Docking Simulation<br/>Molecular Structure<br/>Muscle Contraction--drug effects<br/>Muscle, Smooth--drug effects<br/>Phosphodiesterase 4 Inhibitors--chemical synthesis<br/>Pyrimidines--chemical synthesis<br/>Rats<br/>Rats, Sprague-Dawley<br/>Structure-Activity Relationship<br/>Trachea--drug effects<br/>Triazoles--chemical synthesis