TY - GEN AU - Taft,Joseph M AU - Georgeon,Sandrine AU - Allen,Chris AU - Reckel,Sina AU - DeSautelle,Joseph AU - Hantschel,Oliver AU - Georgiou,George AU - Iverson,Brent L TI - Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity SN - 1554-8937 PY - 2020///0406 KW - Antibodies KW - chemistry KW - Cell Adhesion Molecules KW - immunology KW - Dasatinib KW - pharmacology KW - Drug Resistance KW - physiology KW - Flow Cytometry KW - methods KW - Fluorescent Dyes KW - High-Throughput Screening Assays KW - Humans KW - Imidazoles KW - Machine Learning KW - Mutation KW - Phosphorylation KW - drug effects KW - Proof of Concept Study KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins c-abl KW - antagonists & inhibitors KW - Pyridazines KW - Recombinant Fusion Proteins KW - Saccharomyces cerevisiae KW - Saccharomyces cerevisiae Proteins KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acschembio.9b00283 ER -