TY - GEN AU - Chen,Biao AU - Lu,Kai-Hang AU - Ni,Qu-Bo AU - Li,Qing-Xian AU - Gao,Hui AU - Wang,Hui AU - Chen,Liao-Bin TI - Prenatal nicotine exposure increases osteoarthritis susceptibility in male elderly offspring rats via low-function programming of the TGFβ signaling pathway SN - 1879-3169 PY - 2019///0916 KW - Age Factors KW - Aggrecans KW - metabolism KW - Animals KW - Apoptosis KW - drug effects KW - Caspase 3 KW - Caspase 8 KW - Chondrocytes KW - Chondrogenesis KW - Collagen Type II KW - Female KW - Gestational Age KW - Interleukin-1 KW - Interleukin-6 KW - Joints KW - Male KW - Maternal Exposure KW - Matrix Metalloproteinase 13 KW - Matrix Metalloproteinase 3 KW - Nicotine KW - toxicity KW - Nicotinic Agonists KW - Osteoarthritis KW - chemically induced KW - Pregnancy KW - Prenatal Exposure Delayed Effects KW - Rats, Wistar KW - Risk Factors KW - Sex Factors KW - Signal Transduction KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.toxlet.2019.06.010 ER -