TY - GEN AU - Noel,Marcus AU - O'Reilly,Eileen M AU - Wolpin,Brian M AU - Ryan,David P AU - Bullock,Andrea J AU - Britten,Carolyn D AU - Linehan,David C AU - Belt,Brian A AU - Gamelin,Eric C AU - Ganguly,Bishu AU - Yin,Donghua AU - Joh,Tenshang AU - Jacobs,Ira A AU - Taylor,Carrie T AU - Lowery,Maeve A TI - Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma SN - 1573-0646 PY - 2021///0601 KW - Adenocarcinoma KW - drug therapy KW - Aged KW - Albumins KW - therapeutic use KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Pancreatic Ductal KW - Chemokine CCL2 KW - antagonists & inhibitors KW - Cohort Studies KW - Deoxycytidine KW - analogs & derivatives KW - Female KW - Humans KW - Male KW - Middle Aged KW - Paclitaxel KW - Pancreatic Neoplasms KW - Prognosis KW - Pyrrolidines KW - Small Molecule Libraries KW - Tumor Microenvironment KW - drug effects KW - Gemcitabine N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10637-019-00830-3 ER -