TY  - GEN
AU  - Pentinmikko,Nalle
AU  - Iqbal,Sharif
AU  - Mana,Miyeko
AU  - Andersson,Simon
AU  - Cognetta,Armand B
AU  - Suciu,Radu M
AU  - Roper,Jatin
AU  - Luopajärvi,Kalle
AU  - Markelin,Eino
AU  - Gopalakrishnan,Swetha
AU  - Smolander,Olli-Pekka
AU  - Naranjo,Santiago
AU  - Saarinen,Tuure
AU  - Juuti,Anne
AU  - Pietiläinen,Kirsi
AU  - Auvinen,Petri
AU  - Ristimäki,Ari
AU  - Gupta,Nitin
AU  - Tammela,Tuomas
AU  - Jacks,Tyler
AU  - Sabatini,David M
AU  - Cravatt,Benjamin F
AU  - Yilmaz,Ömer H
AU  - Katajisto,Pekka
TI  - Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
SN  - 1476-4687
PY  - 2019///1007
KW  - Aging
KW  - physiology
KW  - Animals
KW  - Cellular Senescence
KW  - Esterases
KW  - antagonists & inhibitors
KW  - Female
KW  - Humans
KW  - Intestinal Mucosa
KW  - pathology
KW  - Male
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - metabolism
KW  - Mice
KW  - PPAR alpha
KW  - Paneth Cells
KW  - Receptors, G-Protein-Coupled
KW  - Regeneration
KW  - Stem Cell Niche
KW  - Stem Cells
KW  - Wnt Proteins
KW  - Wnt Signaling Pathway
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41586-019-1383-0
ER  -