TY  - GEN
AU  - van Eijk,Ruben P A
AU  - Nikolakopoulos,Stavros
AU  - Roes,Kit C B
AU  - Middelkoop,Bas M
AU  - Ferguson,Toby A
AU  - Shaw,Pamela J
AU  - Leigh,P Nigel
AU  - Al-Chalabi,Ammar
AU  - Eijkemans,Marinus J C
AU  - van den Berg,Leonard H
TI  - Critical design considerations for time-to-event endpoints in amyotrophic lateral sclerosis clinical trials
SN  - 1468-330X
PY  - 2020///0611
KW  - Adult
KW  - Amyotrophic Lateral Sclerosis
KW  - drug therapy
KW  - Clinical Trials as Topic
KW  - methods
KW  - Endpoint Determination
KW  - Female
KW  - Humans
KW  - Male
KW  - Quality of Life
KW  - Research Design
KW  - Riluzole
KW  - therapeutic use
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1136/jnnp-2019-320998
ER  -