Achek, Asma

Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model. [electronic resource] - Journal of medicinal chemistry 07 2019 - 6495-6511 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/acs.jmedchem.9b00061 doi


Animals
Anti-Inflammatory Agents--chemistry
Arthritis, Rheumatoid--drug therapy
Drug Design
Lipopolysaccharides--immunology
Male
Mice
Peptides--chemistry
RAW 264.7 Cells
Rats
Rats, Inbred Lew
Signal Transduction--drug effects
Toll-Like Receptor 4--antagonists & inhibitors
Tumor Necrosis Factor-alpha--immunology