TY  - GEN
AU  - Sumi,Natalia J
AU  - Ctortecka,Claudia
AU  - Hu,Qianqian
AU  - Bryant,Annamarie T
AU  - Fang,Bin
AU  - Remsing Rix,Lily L
AU  - Ayaz,Muhammad
AU  - Kinose,Fumi
AU  - Welsh,Eric A
AU  - Eschrich,Steven A
AU  - Lawrence,Harshani R
AU  - Koomen,John M
AU  - Haura,Eric B
AU  - Rix,Uwe
TI  - Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
SN  - 2451-9448
PY  - 2020///0727
KW  - Anilides
KW  - pharmacology
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - metabolism
KW  - Aurora Kinase B
KW  - Cell Line, Tumor
KW  - Drug Discovery
KW  - Humans
KW  - Lung Neoplasms
KW  - drug therapy
KW  - MAP Kinase Kinase 1
KW  - MAP Kinase Kinase 2
KW  - Organophosphates
KW  - Polypharmacology
KW  - Protein Kinase Inhibitors
KW  - chemistry
KW  - Protein-Tyrosine Kinases
KW  - Pyridines
KW  - Quinazolines
KW  - Quinolines
KW  - Systems Analysis
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.chembiol.2019.06.003
ER  -