Wu, Yun <br/><br/>
Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-  [electronic resource] 

 -  Journal of medicinal chemistry  07 2019 
 - 6083-6101 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.9b00280  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Benzeneacetamides--chemical synthesis<br/>Cell Proliferation--drug effects<br/>Dogs<br/>Drug Discovery<br/>Female<br/>Gastrointestinal Neoplasms--drug therapy<br/>Gastrointestinal Stromal Tumors--drug therapy<br/>Humans<br/>Male<br/>Mice, Inbred BALB C<br/>Models, Molecular<br/>Molecular Structure<br/>Mutation<br/>Protein Binding<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Proto-Oncogene Proteins c-kit--antagonists & inhibitors<br/>Quinolines--chemical synthesis<br/>Rats, Sprague-Dawley<br/>Structure-Activity Relationship<br/>Xenograft Model Antitumor Assays