Rath, Abhijit <br/><br/>
Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells.  [electronic resource] 

 -  Human mutation  11 2019 
 - 2044-2056 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1098-1004 
<br/><br/><label>Standard No.: </label>10.1002/humu.23848  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>CRISPR-Cas Systems<br/>Cell Line, Tumor<br/>Colorectal Neoplasms, Hereditary Nonpolyposis--diagnosis<br/>DNA Damage<br/>DNA Repair<br/>Gene Editing<br/>High-Throughput Nucleotide Sequencing<br/>Human Embryonic Stem Cells--metabolism<br/>Humans<br/>Microsatellite Instability<br/>Models, Molecular<br/>MutS Homolog 2 Protein--chemistry<br/>Mutation, Missense<br/>Protein Conformation<br/>Signal Transduction