Chen, Shulun <br/><br/>
Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors.  [electronic resource] 

 -  European journal of medicinal chemistry  Oct 2019 
 - 38-55 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2019.06.037  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amines--chemical synthesis<br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Drug Screening Assays, Antitumor<br/>Enzyme Inhibitors--chemical synthesis<br/>Female<br/>HEK293 Cells<br/>Humans<br/>Indoleamine-Pyrrole 2,3,-Dioxygenase--antagonists & inhibitors<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Molecular Structure<br/>Oxadiazoles--chemical synthesis<br/>Rats<br/>Rats, Sprague-Dawley<br/>Structure-Activity Relationship