TY  - GEN
AU  - Link,John O
AU  - Taylor,James G
AU  - Trejo-Martin,Alejandra
AU  - Kato,Darryl
AU  - Katana,Ashley A
AU  - Krygowski,Evan S
AU  - Yang,Zheng-Yu
AU  - Zipfel,Sheila
AU  - Cottell,Jeromy J
AU  - Bacon,Elizabeth M
AU  - Tran,Chinh V
AU  - Yang,Cheng Y
AU  - Wang,Yujin
AU  - Wang,Kelly W
AU  - Zhao,Guangyu
AU  - Cheng,Guofeng
AU  - Tian,Yang
AU  - Gong,Ruoyu
AU  - Lee,Yu-Jen
AU  - Yu,Mei
AU  - Gorman,Eric
AU  - Mogalian,Erik
AU  - Perry,Jason K
TI  - Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi
SN  - 1464-3405
PY  - 2020///0922
KW  - Antiviral Agents
KW  - chemical synthesis
KW  - Carbamates
KW  - Dose-Response Relationship, Drug
KW  - Drug Combinations
KW  - Drug Discovery
KW  - Genotype
KW  - Hepacivirus
KW  - drug effects
KW  - Heterocyclic Compounds, 4 or More Rings
KW  - Humans
KW  - Macrocyclic Compounds
KW  - chemistry
KW  - Microbial Sensitivity Tests
KW  - Molecular Structure
KW  - Protease Inhibitors
KW  - Sofosbuvir
KW  - Structure-Activity Relationship
KW  - Sulfonamides
KW  - Tablets
KW  - Viral Nonstructural Proteins
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2019.04.027
ER  -