Link, John O <br/><br/>
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  08 2019 
 - 2415-2427 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2019.04.027  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antiviral Agents--chemical synthesis<br/>Carbamates--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Drug Combinations<br/>Drug Discovery<br/>Genotype<br/>Hepacivirus--drug effects<br/>Heterocyclic Compounds, 4 or More Rings--chemical synthesis<br/>Humans<br/>Macrocyclic Compounds--chemistry<br/>Microbial Sensitivity Tests<br/>Molecular Structure<br/>Protease Inhibitors--chemical synthesis<br/>Sofosbuvir--chemistry<br/>Structure-Activity Relationship<br/>Sulfonamides--chemistry<br/>Tablets--chemistry<br/>Viral Nonstructural Proteins--antagonists & inhibitors