TY - GEN AU - Lam,Hung-Ming AU - Nguyen,Holly M AU - Labrecque,Mark P AU - Brown,Lisha G AU - Coleman,Ilsa M AU - Gulati,Roman AU - Lakely,Bryce AU - Sondheim,Daniel AU - Chatterjee,Payel AU - Marck,Brett T AU - Matsumoto,Alvin M AU - Mostaghel,Elahe A AU - Schweizer,Michael T AU - Nelson,Peter S AU - Corey,Eva TI - Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts SN - 1873-7560 PY - 2021///0318 KW - Animals KW - Benzamides KW - DNA Repair KW - Drug Resistance, Neoplasm KW - Humans KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Nitriles KW - Phenylthiohydantoin KW - analogs & derivatives KW - Prostatic Neoplasms, Castration-Resistant KW - drug therapy KW - Testosterone KW - administration & dosage KW - Time Factors KW - Transcriptome KW - Treatment Failure KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.eururo.2019.05.042 ER -