TY  - GEN
AU  - Choquet,Karine
AU  - Pinard,Maxime
AU  - Yang,Sharon
AU  - Moir,Robyn D
AU  - Poitras,Christian
AU  - Dicaire,Marie-Josée
AU  - Sgarioto,Nicolas
AU  - Larivière,Roxanne
AU  - Kleinman,Claudia L
AU  - Willis,Ian M
AU  - Gauthier,Marie-Soleil
AU  - Coulombe,Benoit
AU  - Brais,Bernard
TI  - The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis
SN  - 1756-6606
PY  - 2020///0526
KW  - Animals
KW  - Base Sequence
KW  - Embryo Loss
KW  - enzymology
KW  - Gene Expression Regulation, Enzymologic
KW  - Gene Knock-In Techniques
KW  - HEK293 Cells
KW  - Hereditary Central Nervous System Demyelinating Diseases
KW  - genetics
KW  - Homozygote
KW  - Humans
KW  - Mice, Inbred C57BL
KW  - Mice, Mutant Strains
KW  - Motor Activity
KW  - Mutation
KW  - Myelin Sheath
KW  - metabolism
KW  - RNA Polymerase III
KW  - RNA, Messenger
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s13041-019-0479-7
ER  -