Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. [electronic resource]
- Human molecular genetics 07 2019
- 2255-2270 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1460-2083
10.1093/hmg/ddz050 doi
Animals Cell Differentiation Dermis--drug effects HeLa Cells Humans Interleukin-1--genetics Isothiocyanates--therapeutic use Kelch-Like ECH-Associated Protein 1--metabolism Keratin-16--genetics Keratin-9--genetics Keratinocytes--cytology Keratins--metabolism Keratoderma, Palmoplantar--drug therapy Mice Mice, Inbred C57BL Mice, Knockout Mutation Mutation, Missense NF-E2-Related Factor 2--metabolism Signal Transduction Sulfoxides Tissue Array Analysis