TY - GEN AU - Ielo,Laura AU - Deri,Batel AU - Germanò,Maria Paola AU - Vittorio,Serena AU - Mirabile,Salvatore AU - Gitto,Rosaria AU - Rapisarda,Antonio AU - Ronsisvalle,Simone AU - Floris,Sonia AU - Pazy,Yael AU - Fais,Antonella AU - Fishman,Ayelet AU - De Luca,Laura TI - Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile SN - 1768-3254 PY - 2019///1002 KW - Agaricus KW - chemistry KW - Antineoplastic Agents KW - chemical synthesis KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Crystallography, X-Ray KW - Dose-Response Relationship, Drug KW - Drug Design KW - Drug Screening Assays, Antitumor KW - Enzyme Inhibitors KW - Humans KW - Models, Molecular KW - Molecular Structure KW - Monophenol Monooxygenase KW - antagonists & inhibitors KW - Piperazines KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ejmech.2019.06.019 ER -