Ielo, Laura

Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile. [electronic resource] - European journal of medicinal chemistry Sep 2019 - 380-389 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2019.06.019 doi


Agaricus--chemistry
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Design
Drug Screening Assays, Antitumor
Enzyme Inhibitors--chemical synthesis
Humans
Models, Molecular
Molecular Structure
Monophenol Monooxygenase--antagonists & inhibitors
Piperazines--chemical synthesis
Structure-Activity Relationship