TY  - GEN
AU  - Kümler,Iben
AU  - Balslev,Eva
AU  - Stenvang,Jan
AU  - Brünner,Nils
AU  - Ejlertsen,Bent
AU  - Jakobsen,Erik Hugger
AU  - Nielsen,Dorte Lisbet
TI  - Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene
SN  - 1471-2407
PY  - 2019///1223
KW  - Aged
KW  - Antineoplastic Agents
KW  - therapeutic use
KW  - Biomarkers, Pharmacological
KW  - Breast Neoplasms
KW  - diagnosis
KW  - DNA Topoisomerases, Type I
KW  - genetics
KW  - Drug Therapy, Combination
KW  - Female
KW  - Gene Dosage
KW  - Humans
KW  - Irinotecan
KW  - Middle Aged
KW  - Predictive Value of Tests
KW  - Prognosis
KW  - Receptor, ErbB-2
KW  - metabolism
KW  - Topoisomerase I Inhibitors
KW  - Trastuzumab
KW  - Treatment Outcome
N1  - Publication Type: Clinical Trial, Phase II; Journal Article
UR  - https://doi.org/10.1186/s12885-019-5788-9
ER  -