Birkinshaw, Richard W <br/><br/>
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.  [electronic resource] 

 -  Nature communications  06 2019 
 - 2385 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/s41467-019-10363-1  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--metabolism<br/>Bridged Bicyclo Compounds, Heterocyclic--metabolism<br/>Crystallization<br/>Crystallography, X-Ray<br/>Drug Resistance, Neoplasm--genetics<br/>Humans<br/>Leukemia, Lymphocytic, Chronic, B-Cell--drug therapy<br/>Mutation<br/>Protein Binding<br/>Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors<br/>Sulfonamides--metabolism<br/>Surface Plasmon Resonance