TY - GEN AU - Purgatorio,Rosa AU - de Candia,Modesto AU - Catto,Marco AU - Carrieri,Antonio AU - Pisani,Leonardo AU - De Palma,Annalisa AU - Toma,Maddalena AU - Ivanova,Olga A AU - Voskressensky,Leonid G AU - Altomare,Cosimo D TI - Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease SN - 1768-3254 PY - 2019///0725 KW - Amyloid beta-Peptides KW - metabolism KW - Azepines KW - chemical synthesis KW - Butyrylcholinesterase KW - chemistry KW - Catalytic Domain KW - Cell Line, Tumor KW - Cholinesterase Inhibitors KW - Dose-Response Relationship, Drug KW - Drug Design KW - Free Radical Scavengers KW - Humans KW - Indoles KW - Molecular Docking Simulation KW - Molecular Structure KW - Neuroprotective Agents KW - Peptide Fragments KW - Protein Binding KW - drug effects KW - Protein Multimerization KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ejmech.2019.05.062 ER -