Purgatorio, Rosa <br/><br/>
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease.  [electronic resource] 

 -  European journal of medicinal chemistry  Sep 2019 
 - 414-424 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2019.05.062  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyloid beta-Peptides--metabolism<br/>Azepines--chemical synthesis<br/>Butyrylcholinesterase--chemistry<br/>Catalytic Domain<br/>Cell Line, Tumor<br/>Cholinesterase Inhibitors--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Free Radical Scavengers--chemical synthesis<br/>Humans<br/>Indoles--chemical synthesis<br/>Molecular Docking Simulation<br/>Molecular Structure<br/>Neuroprotective Agents--chemical synthesis<br/>Peptide Fragments--metabolism<br/>Protein Binding--drug effects<br/>Protein Multimerization--drug effects<br/>Structure-Activity Relationship