TY - GEN AU - Torres,Sandra Elizabeth AU - Gallagher,Ciara M AU - Plate,Lars AU - Gupta,Meghna AU - Liem,Christina R AU - Guo,Xiaoyan AU - Tian,Ruilin AU - Stroud,Robert M AU - Kampmann,Martin AU - Weissman,Jonathan S AU - Walter,Peter TI - Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether SN - 2050-084X PY - 2020///0225 KW - ATP-Binding Cassette Transporters KW - metabolism KW - Activating Transcription Factor 6 KW - antagonists & inhibitors KW - CRISPR-Cas Systems KW - genetics KW - Endoplasmic Reticulum KW - drug effects KW - HEK293 Cells KW - Hep G2 Cells KW - Humans KW - Organelles KW - Peroxisomes KW - Phenotype KW - Protein Binding KW - Small Molecule Libraries KW - pharmacology KW - Unfolded Protein Response N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7554/eLife.46595 ER -