TY - GEN AU - Mao,Xu AU - Wang,Jian AU - Wang,Qian AU - Yang,Lan AU - Li,Yilin AU - Lin,Hao AU - Peng,Ying AU - Zheng,Jiang TI - Nitidine Chloride-Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism SN - 1521-009X PY - 2020///0420 KW - Benzophenanthridines KW - pharmacology KW - Cytochrome P-450 CYP1A1 KW - antagonists & inhibitors KW - Cytochrome P-450 CYP1A2 KW - metabolism KW - Cytochrome P-450 CYP1B1 KW - Drug Interactions KW - Drugs, Chinese Herbal KW - Enzyme Assays KW - Estradiol KW - Estrogens, Catechol KW - Humans KW - Inhibitory Concentration 50 KW - MCF-7 Cells KW - Metabolic Networks and Pathways KW - drug effects KW - Molecular Docking Simulation KW - Mutagenicity Tests KW - Plant Roots KW - chemistry KW - Protein Binding KW - Recombinant Proteins KW - Serine KW - Zanthoxylum N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/dmd.119.086892 ER -