Rosenthal, G J <br/><br/>
Suppression of B cell function by methotrexate and trimetrexate. Evidence for inhibition of purine biosynthesis as a major mechanism of action.  [electronic resource] 

 -  Journal of immunology (Baltimore, Md. : 1950)  Jul 1988 
 - 410-6 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-1767 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibody Formation--drug effects<br/>B-Lymphocytes--drug effects<br/>Cell Differentiation--drug effects<br/>Female<br/>Folic Acid Antagonists--pharmacology<br/>Immunoglobulins--biosynthesis<br/>Immunosuppressive Agents--pharmacology<br/>Kinetics<br/>Lymphocyte Activation--drug effects<br/>Methotrexate--pharmacology<br/>Mice<br/>Purines--antagonists & inhibitors<br/>Quinazolines--pharmacology<br/>Trimetrexate