Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. [electronic resource]
- Structure (London, England : 1993) 07 2019
- 1124-1136.e4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-4186
10.1016/j.str.2019.04.009 doi
Acetyl Coenzyme A--chemistry Catalytic Domain Cloning, Molecular Coenzyme A--chemistry Cryoelectron Microscopy Escherichia coli--genetics Gene Expression Genetic Vectors--chemistry Humans Kinetics Models, Molecular Protein Binding Protein Conformation, alpha-Helical Protein Conformation, beta-Strand Protein Interaction Domains and Motifs Protein Multimerization Protein Subunits--chemistry Pyruvate Dehydrogenase Complex--chemistry Recombinant Proteins--chemistry Substrate Specificity Thermodynamics