TY - GEN AU - Yang,Chuan AU - Lou,Weiyang AU - Zhong,Guansheng AU - Lee,Ashlynn AU - Leong,Jiayu AU - Chin,Willy AU - Ding,Bisha AU - Bao,Chang AU - Tan,Jeremy P K AU - Pu,Qinqin AU - Gao,Shujun AU - Xu,Liang AU - Hsu,Li Yang AU - Wu,Min AU - Hedrick,James L AU - Fan,Weimin AU - Yang,Yi Yan TI - Degradable antimicrobial polycarbonates with unexpected activity and selectivity for treating multidrug-resistant Klebsiella pneumoniae lung infection in mice SN - 1878-7568 PY - 2020///0811 KW - Animals KW - Anti-Bacterial Agents KW - pharmacology KW - Anti-Infective Agents KW - Biocompatible Materials KW - Cell Line KW - Cell Membrane KW - metabolism KW - Cytosol KW - Drug Resistance, Multiple, Bacterial KW - Epithelial Cells KW - drug effects KW - Female KW - Guanidine KW - Humans KW - Imipenem KW - Kinetics KW - Klebsiella Infections KW - drug therapy KW - Klebsiella pneumoniae KW - Lung Diseases KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred ICR KW - Microbial Sensitivity Tests KW - Pneumonia, Bacterial KW - Polycarboxylate Cement KW - Polymers KW - chemistry KW - Protein Binding N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.actbio.2019.05.057 ER -