TY - GEN AU - Bharathy,Narendra AU - Berlow,Noah E AU - Wang,Eric AU - Abraham,Jinu AU - Settelmeyer,Teagan P AU - Hooper,Jody E AU - Svalina,Matthew N AU - Bajwa,Zia AU - Goros,Martin W AU - Hernandez,Brian S AU - Wolff,Johannes E AU - Pal,Ranadip AU - Davies,Angela M AU - Ashok,Arya AU - Bushby,Darnell AU - Mancini,Maria AU - Noakes,Christopher AU - Goodwin,Neal C AU - Ordentlich,Peter AU - Keck,James AU - Hawkins,Douglas S AU - Rudzinski,Erin R AU - Mansoor,Atiya AU - Perkins,Theodore J AU - Vakoc,Christopher R AU - Michalek,Joel E AU - Keller,Charles TI - Preclinical rationale for entinostat in embryonal rhabdomyosarcoma SN - 2044-5040 PY - 2020///0504 KW - Adolescent KW - Animals KW - Antineoplastic Agents, Phytogenic KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - Benzamides KW - CRISPR-Cas Systems KW - Cell Differentiation KW - drug effects KW - Cell Line, Tumor KW - Cellular Reprogramming KW - Child KW - Child, Preschool KW - Drug Screening Assays, Antitumor KW - Female KW - Histone Deacetylase 1 KW - antagonists & inhibitors KW - Histone Deacetylase Inhibitors KW - Humans KW - Male KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Pyridines KW - RNA-Seq KW - Rhabdomyosarcoma, Alveolar KW - drug therapy KW - Rhabdomyosarcoma, Embryonal KW - Tumor Burden KW - Tumor Microenvironment KW - Vincristine KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s13395-019-0198-x ER -