Pak, Ekaterina

A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma. [electronic resource] - Neuro-oncology 09 2019 - 1150-1163 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1523-5866

10.1093/neuonc/noz089 doi


Anilides
Animals
Biphenyl Compounds
Cell Line, Tumor
Cell Survival--drug effects
Cerebellar Neoplasms--drug therapy
Drug Resistance, Neoplasm--genetics
Hedgehog Proteins--drug effects
High-Throughput Screening Assays
Histone Deacetylase Inhibitors--pharmacology
Hydroxamic Acids--pharmacology
Inhibitory Concentration 50
Medulloblastoma--drug therapy
Mice
Proteins--genetics
Pyridines
Repressor Proteins--genetics
Signal Transduction
Smoothened Receptor--antagonists & inhibitors