Cui, Ning <br/><br/>
Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.  [electronic resource] 

 -  Journal of cellular and molecular medicine  07 2019 
 - 4627-4639 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1582-4934 
<br/><br/><label>Standard No.: </label>10.1111/jcmm.14346  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cardiotoxicity--enzymology<br/>Cell Death--drug effects<br/>Cell Differentiation<br/>Cells, Cultured<br/>DNA Damage<br/>DNA Topoisomerases, Type II--metabolism<br/>Doxorubicin--adverse effects<br/>Humans<br/>Induced Pluripotent Stem Cells--cytology<br/>Models, Biological<br/>Myocytes, Cardiac--enzymology<br/>Poly-ADP-Ribose Binding Proteins--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Time Factors