Kemeny, N <br/><br/>
Implementation of the group sequential methodology in a randomized trial in metastatic colorectal carcinoma.  [electronic resource] 

 -  American journal of clinical oncology  Feb 1988 
 - 66-72 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0277-3732 
<br/><br/><label>Standard No.: </label>10.1097/00000421-198802000-00014  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Antineoplastic Combined Chemotherapy Protocols--therapeutic use<br/>Clinical Trials as Topic<br/>Colonic Neoplasms--drug therapy<br/>Female<br/>Fluorouracil--administration & dosage<br/>Humans<br/>Leukocyte Count<br/>Male<br/>Methotrexate--administration & dosage<br/>Middle Aged<br/>Prognosis<br/>Prospective Studies<br/>Random Allocation<br/>Semustine--administration & dosage<br/>Streptozocin--administration & dosage<br/>Vincristine--administration & dosage