TY  - GEN
AU  - Bi,Silei
AU  - Chen,Kai
AU  - Feng,Liying
AU  - Fu,Guofeng
AU  - Yang,Qianying
AU  - Deng,Manman
AU  - Zhao,Haijun
AU  - Li,Zhifeng
AU  - Yu,Lian
AU  - Fang,Zhihong
AU  - Xu,Bing
TI  - Napabucasin (BBI608) eliminate AML cells in vitro and in vivo via inhibition of Stat3 pathway and induction of DNA damage
SN  - 1879-0712
PY  - 2019///1220
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Benzofurans
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - DNA Damage
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Female
KW  - G1 Phase Cell Cycle Checkpoints
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - drug therapy
KW  - Male
KW  - Membrane Potential, Mitochondrial
KW  - Mice
KW  - Middle Aged
KW  - Naphthoquinones
KW  - Resting Phase, Cell Cycle
KW  - STAT3 Transcription Factor
KW  - metabolism
KW  - Time Factors
KW  - Xenograft Model Antitumor Assays
KW  - Young Adult
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.ejphar.2019.05.020
ER  -