O'Reilly, Molly <br/><br/>
Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.  [electronic resource] 

 -  Journal of medicinal chemistry  06 2019 
 - 5312-5329 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.8b01325  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoglycosides--adverse effects<br/>Animals<br/>Carvedilol--chemical synthesis<br/>Chemistry Techniques, Synthetic<br/>Cytoprotection--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Electrophysiological Phenomena--drug effects<br/>Hair Cells, Auditory--cytology<br/>Mechanotransduction, Cellular--drug effects<br/>Mice<br/>Zebrafish