Loizou, Evangelia

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1. [electronic resource] - Cancer discovery 07 2019 - 962-979 p. digital

Publication Type: News; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2159-8290

10.1158/2159-8290.CD-18-1391 doi


Animals
Cell Line, Tumor
Cell Plasticity--genetics
Forkhead Transcription Factors--genetics
Gain of Function Mutation
Gene Expression Profiling
Humans
Leukemia, Myeloid, Acute--genetics
Mice
Mice, Inbred NOD
Mice, Knockout
Mice, SCID
Mice, Transgenic
Neoplastic Stem Cells--metabolism
Pluripotent Stem Cells--metabolism
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays