A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1. [electronic resource]
- Cancer discovery 07 2019
- 962-979 p. digital
Publication Type: News; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2159-8290
10.1158/2159-8290.CD-18-1391 doi
Animals Cell Line, Tumor Cell Plasticity--genetics Forkhead Transcription Factors--genetics Gain of Function Mutation Gene Expression Profiling Humans Leukemia, Myeloid, Acute--genetics Mice Mice, Inbred NOD Mice, Knockout Mice, SCID Mice, Transgenic Neoplastic Stem Cells--metabolism Pluripotent Stem Cells--metabolism Tumor Suppressor Protein p53--genetics Xenograft Model Antitumor Assays