TY - GEN AU - Wang,Zhenxun AU - Yip,Lian Yee AU - Lee,Jia Hui Jane AU - Wu,Zhengwei AU - Chew,Hui Yi AU - Chong,Pooi Kiat William AU - Teo,Chin Chye AU - Ang,Heather Yin-Kuan AU - Peh,Kai Lay Esther AU - Yuan,Ju AU - Ma,Siming AU - Choo,Li Shi Kimberly AU - Basri,Nurhidayah AU - Jiang,Xia AU - Yu,Qiang AU - Hillmer,Axel M AU - Lim,Wan Teck AU - Lim,Tony Kiat Hon AU - Takano,Angela AU - Tan,Eng Huat AU - Tan,Daniel Shao Weng AU - Ho,Ying Swan AU - Lim,Bing AU - Tam,Wai Leong TI - Methionine is a metabolic dependency of tumor-initiating cells SN - 1546-170X PY - 2019///0710 KW - Animals KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Differentiation KW - Cell Line, Tumor KW - Female KW - Gene Knockdown Techniques KW - Glycine Dehydrogenase (Decarboxylating) KW - antagonists & inhibitors KW - Humans KW - Lung Neoplasms KW - Male KW - Metabolic Networks and Pathways KW - Metabolomics KW - Methionine KW - metabolism KW - Methionine Adenosyltransferase KW - Mice KW - Neoplastic Stem Cells KW - drug effects KW - S-Adenosylmethionine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41591-019-0423-5 ER -