DNA-PKc deficiency drives pre-malignant transformation by reducing DNA repair capacity in concert with reprogramming the epigenome in human bronchial epithelial cells. [electronic resource]
- DNA repair 07 2019
- 1-9 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1568-7856
10.1016/j.dnarep.2019.04.006 doi
Bleomycin--pharmacology Bronchi--cytology Cell Line, Tumor Cell Transformation, Neoplastic--genetics DNA Methylation DNA Repair DNA-Activated Protein Kinase--genetics Epigenesis, Genetic Epithelial Cells--drug effects Haploinsufficiency Humans Promoter Regions, Genetic Respiratory Mucosa--metabolism