TY - GEN AU - Mandal,Rajarsi AU - Samstein,Robert M AU - Lee,Ken-Wing AU - Havel,Jonathan J AU - Wang,Hao AU - Krishna,Chirag AU - Sabio,Erich Y AU - Makarov,Vladimir AU - Kuo,Fengshen AU - Blecua,Pedro AU - Ramaswamy,Apoorva T AU - Durham,Jennifer N AU - Bartlett,Bjarne AU - Ma,Xiaoxiao AU - Srivastava,Raghvendra AU - Middha,Sumit AU - Zehir,Ahmet AU - Hechtman,Jaclyn F AU - Morris,Luc Gt AU - Weinhold,Nils AU - Riaz,Nadeem AU - Le,Dung T AU - Diaz,Luis A AU - Chan,Timothy A TI - Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response SN - 1095-9203 PY - 2019///1031 KW - Animals KW - Antibodies KW - therapeutic use KW - DNA Mismatch Repair KW - genetics KW - Genetic Variation KW - Immunotherapy KW - methods KW - Melanoma, Experimental KW - Mice KW - Microsatellite Instability KW - MutS Homolog 2 Protein KW - Mutation KW - Neoplasms KW - Programmed Cell Death 1 Receptor KW - antagonists & inhibitors KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.aau0447 ER -