TY  - GEN
AU  - Chen,Xufeng
AU  - Glytsou,Christina
AU  - Zhou,Hua
AU  - Narang,Sonali
AU  - Reyna,Denis E
AU  - Lopez,Andrea
AU  - Sakellaropoulos,Theodore
AU  - Gong,Yixiao
AU  - Kloetgen,Andreas
AU  - Yap,Yoon Sing
AU  - Wang,Eric
AU  - Gavathiotis,Evripidis
AU  - Tsirigos,Aristotelis
AU  - Tibes,Raoul
AU  - Aifantis,Iannis
TI  - Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment
SN  - 2159-8290
PY  - 2020///0824
KW  - Animals
KW  - Antineoplastic Agents
KW  - metabolism
KW  - Apoptosis
KW  - drug effects
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Clustered Regularly Interspaced Short Palindromic Repeats
KW  - Drug Resistance, Neoplasm
KW  - Endopeptidase Clp
KW  - antagonists & inhibitors
KW  - GTP Phosphohydrolases
KW  - biosynthesis
KW  - HEK293 Cells
KW  - HeLa Cells
KW  - Humans
KW  - K562 Cells
KW  - Leukemia, Myeloid, Acute
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Mitochondria
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Sulfonamides
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1158/2159-8290.CD-19-0117
ER  -