Chen, Xufeng <br/><br/>
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.  [electronic resource] 

 -  Cancer discovery  07 2019 
 - 890-909 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>2159-8290 
<br/><br/><label>Standard No.: </label>10.1158/2159-8290.CD-19-0117  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--metabolism<br/>Apoptosis--drug effects<br/>Bridged Bicyclo Compounds, Heterocyclic--pharmacology<br/>Cell Line, Tumor<br/>Clustered Regularly Interspaced Short Palindromic Repeats<br/>Drug Resistance, Neoplasm<br/>Endopeptidase Clp--antagonists & inhibitors<br/>GTP Phosphohydrolases--biosynthesis<br/>HEK293 Cells<br/>HeLa Cells<br/>Humans<br/>K562 Cells<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Mice<br/>Mice, Inbred NOD<br/>Mice, SCID<br/>Mitochondria--drug effects<br/>Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors<br/>Sulfonamides--pharmacology<br/>Xenograft Model Antitumor Assays