TY - GEN AU - Kurimchak,Alison M AU - Shelton,Claude AU - Herrera-Montávez,Carlos AU - Duncan,Kelly E AU - Chernoff,Jonathan AU - Duncan,James S TI - Intrinsic Resistance to MEK Inhibition through BET Protein-Mediated Kinome Reprogramming in NF1-Deficient Ovarian Cancer SN - 1557-3125 PY - 2020///0416 KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Drug Resistance, Neoplasm KW - drug effects KW - Drug Therapy, Combination KW - Female KW - Humans KW - MAP Kinase Kinase 1 KW - MAP Kinase Signaling System KW - Neurofibromin 1 KW - deficiency KW - Ovarian Neoplasms KW - drug therapy KW - Protein Kinase Inhibitors KW - pharmacology KW - Receptor Protein-Tyrosine Kinases KW - Signal Transduction KW - Transcription Factors KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1541-7786.MCR-18-1332 ER -