TY - GEN AU - Wu,Hao AU - Huang,Yulin AU - Tian,Xinyu AU - Zhang,Zuoxia AU - Zhang,Ying AU - Mao,Yanting AU - Wang,Chenchen AU - Yang,Shuai AU - Liu,Yue AU - Zhang,Wei AU - Ma,Zhengliang TI - Preoperative anxiety-induced glucocorticoid signaling reduces GABAergic markers in spinal cord and promotes postoperative hyperalgesia by affecting neuronal PAS domain protein 4 SN - 1744-8069 PY - 2020///0526 KW - Animals KW - Anxiety KW - complications KW - Basic Helix-Loop-Helix Transcription Factors KW - metabolism KW - Biomarkers KW - Corticosterone KW - blood KW - Dependovirus KW - Down-Regulation KW - drug effects KW - Glucocorticoids KW - Hyperalgesia KW - Injections, Spinal KW - Male KW - Mifepristone KW - pharmacology KW - Neurons KW - Postoperative Care KW - Preoperative Care KW - RNA Interference KW - RNA, Messenger KW - genetics KW - Rats, Sprague-Dawley KW - Signal Transduction KW - Spinal Cord KW - Spironolactone KW - Stress, Psychological KW - Up-Regulation KW - gamma-Aminobutyric Acid N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1177/1744806919850383 ER -