TY - GEN AU - Eldirany,Sherif A AU - Ho,Minh AU - Hinbest,Alexander J AU - Lomakin,Ivan B AU - Bunick,Christopher G TI - Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly SN - 1460-2075 PY - 2020///0107 KW - Amino Acid Substitution KW - Circular Dichroism KW - Crystallography, X-Ray KW - Cytoskeleton KW - chemistry KW - Dynamic Light Scattering KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Intermediate Filament Proteins KW - Keratin-1 KW - Keratin-10 KW - Models, Molecular KW - Mutation, Missense KW - Protein Folding KW - Protein Interaction Domains and Motifs KW - genetics KW - Protein Multimerization KW - physiology KW - Protein Structure, Quaternary KW - Protein Structure, Secondary KW - Skin Diseases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.15252/embj.2018100741 ER -