Curcumin induces apoptosis in JAK2-mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways. [electronic resource]
- Journal of cellular and molecular medicine 06 2019
- 4349-4357 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1582-4934
10.1111/jcmm.14326 doi
Adult Aged Aged, 80 and over Antineoplastic Agents--pharmacology Apoptosis Biomarkers, Tumor Case-Control Studies Cell Movement Cell Proliferation Curcumin--pharmacology Female Follow-Up Studies Gene Expression Regulation, Neoplastic Humans Janus Kinase 2--antagonists & inhibitors Leukemia, Erythroblastic, Acute--drug therapy Leukocytes, Mononuclear--drug effects Male Mechanistic Target of Rapamycin Complex 1--antagonists & inhibitors Middle Aged Mutation Myeloproliferative Disorders--drug therapy Phosphorylation STAT Transcription Factors--antagonists & inhibitors Signal Transduction Tumor Cells, Cultured Young Adult