TY - GEN AU - Wang,Zicheng AU - Feng,Jiannan AU - Yu,Jiyun AU - Chen,Guozhu TI - FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation SN - 1477-9137 PY - 2020///0723 KW - Animals KW - Cell Line, Tumor KW - Female KW - HEK293 Cells KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Necroptosis KW - physiology KW - Phosphorylation KW - Protein Kinases KW - metabolism KW - Receptor-Interacting Protein Serine-Threonine Kinases KW - Receptors, Tumor Necrosis Factor, Type I KW - Signal Transduction KW - Systemic Inflammatory Response Syndrome KW - TOR Serine-Threonine Kinases KW - Tacrolimus Binding Protein 1A N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1242/jcs.227777 ER -