TY - GEN AU - Rottensteiner,Hanspeter AU - Kaufmann,Stefan AU - Rathgeb,Anna AU - Kink,Barbara AU - Plaimauer,Barbara AU - Matthiessen,Peter AU - Hann,Stephan AU - Scheiflinger,Friedrich TI - Temperature-dependent irreversible conformational change of recombinant ADAMTS13 upon metal ion chelation SN - 1538-7836 PY - 2020///0630 KW - ADAMTS13 Protein KW - antagonists & inhibitors KW - Calcium KW - metabolism KW - Catalytic Domain KW - drug effects KW - Chelating Agents KW - pharmacology KW - Citric Acid KW - Dynamic Light Scattering KW - Enzyme Stability KW - Fluorescence Resonance Energy Transfer KW - Humans KW - In Vitro Techniques KW - Mass Spectrometry KW - Protein Conformation KW - Purpura, Thrombotic Thrombocytopenic KW - blood KW - Recombinant Proteins KW - chemistry KW - Spectroscopy, Fourier Transform Infrared KW - Temperature KW - Zinc N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/jth.14440 ER -